Severe Obstructive Physiology on the Ventilator: Peak Pressure, ASV, and pH Targets
Severe obstructive physiology on the ventilator is an area I’d like to better understand, especially COPD/asthma patients with high airway resistance, prolonged time constants, dynamic hyperinflation, and auto-PEEP.
A lot of great ventilator discussion focuses on ARDS, PEEP, oxygenation, and synchrony, but I’d love to hear more expert thoughts on the obstructive side.
Specifically, how do you approach high peak pressures in these patients? In volume-targeted modes, especially on transport ventilators like the Hamilton T1, there are times where the pressure limit may need to be raised to deliver an appropriate tidal volume when resistance is very high. My understanding is that the key is not peak pressure alone, but whether plateau pressure/driving pressure, delivered tidal volume, expiratory flow return, auto-PEEP, and hemodynamics suggest unsafe alveolar distension or worsening dynamic hyperinflation.
I’m also curious about ASV in obstructive patients. I realize many clinicians consider ASV controversial or often avoid it…



Brian out of curiosity are you using volumetric CO2 with your Hamilton T1 as a flight paramedic?